Research lines

• The expression and distribution of the "leakage" two-pore-domain potassium channels (K2P) in the Autonomic Nervous System.
 
• The properties of K2P potassium channels and currents in parasympathetic neurons from the Intracardiac ganglion (IG).
 
• The properties of K2P potassium channels and currents in sympathetic neurons from the superior cervical ganglion (SCG) and nodose ganglion (NG).
 
• The modulation of K2P potassium channels by muscarinic agonists, nootropic agents and other second messenger pathways.
 
• The role of K2P channels in the resting membrane potential and excitability of neurons.
 
• The action of clinically appealing drugs such as linopirdine, XE991, riluzole, fluoxetine or valproate on K2P channels but also on other neuronal excitability related channels and currents (HCN, KCNQ, persistent sodium currents...).

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